Ahem...
I may seem like the nerd but..

Some spiders like the black widow and the brown recluse are the two most poisonous spiders in I think North America. They’re bite will hurt for a couple of days and you’re feeling bad after the bite. You should get treatment. Also the spider’s cobwebs are stronger than a bulletproof vest
But those spiders only exist in North America. And other spiders CAN bite but it won’t be that painful as the brown recluse and the black widow’s bite